Para-Aminobenzoic Acid (PABA) has been called the anti-gray hair vitamin and is considered one of the lesser known members of the vitamin B complex family (despite the fact that it’s not really a vitamin at all).  PABA is a non-protein amino acid and isn’t essential in the human body.  It can be found in foods such as liver, whole grain, yeast, and kidney and is listed as an active ingredient in several popular herbal hair loss treatments such as Provillusfor women and Procerin. 

The potassium salt in PABA called POTABA is available on prescription. POTABA is indicated for Peyronie’s Disease and scleroderma. The dose for Peyronie’s disease and scleroderma is very high (12 grams daily in 4 to 5 distributions) and must only be used under medical supervision. Because of the high doses needed to achieve clinical efficacy, patient compliance is typically poor.

But can PABA actually treat male pattern baldnessor genetic female hair loss?

Some tests conclude that PABA when combined with other elements such as folate, biotin, and pantothenic acid, may restore pre-maturely graying hair to its natural color.  Some anecdotal reports suggest it might also stop hair loss, however; there are at least as many reports that contradict this.  Moreover, we haven’t seen any evidence to suggest it can stimulate new hair growth or hair regrowth.

PABA comes in doses of 100mg, 250mg, and 500mg as a standalone product.  However, since no formal clinical studies have been performed on PABA for hair loss, a suitable dosage is mostly speculation.  Additionally, since no regulations have been placed on herbal medication, one should proceed with extreme caution before taking any herbal supplement.  Consulting with a doctor is advised.

Side Effects and warnings:

Some manufacturers of herbal replacements to medication would have you believe that herbal treatments come without potential side effects.  However, this is a farce. 

The following side effects have been reported from consumers of PABA: Anorexia, vomiting, nausea, hypersensitivity, fever and rash (particularly with larger doses). These symptoms went away when PABA is stopped.

Ironically, Provillusonly includes PABA in the woman’s formula.  However, women should know that pregnant women, nursing mothers, and children should avoid using PABA.

For those with renal disease, PABA should be used with caution.  PABA should be stopped if hypersensitivity develops. Those taking pharmaceutical doses of PABA must be under medical supervision.

One of the more popular hair loss products on the market today for those with thinning hair is Provillus. Available for both men and women, making promises to “re-grow beautiful healthy hair”, this product consists of a topical and oral solution with an FDA approved hair regrowth ingredient and a number of conjectured “all-natural” dihydrotestosterone (DHT) blockers.

Other ingredients that promote a healthy scalp and head of hair are also contained in this product. The theory behind Provillus is to revive the hair follicles with growth stimulators and attack hair loss at its source by blocking DHT.

In order to fully evaluate the efficacy of this product, we must further explore each ingredient to determine whether or not this hair loss treatment delivers what it promises. Below you will find a list of ingredients and information that will help you determine whether or not Provillus is right for you.

Topical Ingredients:

Minoxidil (found in Rogaine, Xandrox and other solutions) is an FDA approved hair growth treatment and many balding men and women use it with great success. This particular ingredient is what allows Provillus to advertise their product as FDA approved.

Azelaic acid has been found to clean the skin and potentially inhibit DHT, the hormone responsible for androgenic alopecia.

Combining these two “forces” therefore in theory, may be a more powerful treatment than minoxidil alone. However, no clinical studies have been performed on azelaic acid as a standalone product therefore, whether or not it can stop hair loss is purely conjecture.

Oral Ingredients:

The Provillus oral solution contains a number of supposed DHT blockers including saw palmetto for hair loss, Vitamin B6 and Zinc, pumpkin or cucurbita maxima, and nettle root. Because evidence exists that these ingredients may be an effective treatment for benign prostatic hypertrophy (BPH), theories have been produced that they might also effectively treat baldness. Though we can appreciate the aspiration for balding men and women to use herbal products as an “all-natural” replacement for Propecia (finasteride), the problem we have is that most of them only contain anecdotal if any evidence at all that they can successfully treat baldness.

Provillus oral solution also contains a number of components that are said to promote healthy hair growth and cleanse the scalp. These include eleuthero, uva-ursi, muria puama, horsetail, para-aminobenzoid acid (PABA), and magnesium. Understand however, that promoting a healthy scalp and hair is not the same as stimulating newhair growth and hair regrowth, nor does it signify an effective hair loss treatment.

Possible Side Effects

The only side effect that we could find listed on the Provillus website is an upset stomach. It is reported that taking it with food often stops this. Be sure to follow the links to the ingredients listed above as many of them also have potentially reported side effects. Consulting with a physician before taking any herbal hair loss medication is advised.

Dosage

Currently there are no standards on dosages of herbal medications in the United States. In addition, no formal clinical studies have been performed on them for treating baldness. Therefore, the suggested daily value listed on the ingredient package is based on something other than government regulation and scientific study.

Costs

A one month supply of Provillus topical and oral supplement for men or for women costs about $50 per month. Discounted prices are available when bought in bulk.

For the cost of Provillus, one can purchase generic finasteride and generic minoxidil which are FDA approved hair loss treatments for safety and efficacy.

Conclusions and Our Opinion

Given that Provillus topical treatment contains FDA approved hair regrowth ingredient minoxidil; we can at least agree that it may have some marginal benefit for men and women suffering from androgenic alopecia. However, due to the lack of compelling evidence in these other conjectured hair loss solutions, it may be more beneficial and cost effective to spend your money on Propecia (finasteride)for men only and Rogaine (minoxidil) that has helped balding men and women worldwide.

Hair loss Myths - What is or isn’t true?

Maybe you’ve heard that wearing a tight baseball cap too often will make you bald or that if you wash your hair too much you’ll suffer hair loss. Well, they’re both old wives’ tales.

So what really causes hair loss and what’s myth?

Brushing to Grow Hair?

The idea of brushing the hair 100 times a day to stimulate the scalp circulation is a fantasy. In fact, if you brush your hair too much, you may end up injuring and losing hair.

This myth stems from the thought that hair loss was due to poor circulation and that brushing or massaging would improve blood flow and nutrition to the follicles. The truth is, bald or not, there’s no major difference in scalp circulation.

Styling and Hair Loss?

There’s some truth and some fiction when it comes to hair styling and Hair Loss.

It is true that certain hair styles, such as corn-rows or tight ponytails, can cause hair loss. These styles put undue tension on the hairs. But as for hair sprays, perm solutions, or coloring resulting in hair loss there’s no truth to that idea. These applications may cause some damage to the hair strands. But the all-important follicles, located under the skin, stay safe.

And what about the idea that haircuts will make your hair grow back thicker and faster? That’s wishful thinking. Everyone’s hair growth and length depends on their own unique hair cycle, which is based on both nutrition and heredity. The longer your growth phase the longer your hair growth.

Blowing away your hair?

What about hair dryers? Are these follicular incinerators?

The good news is there is no evidence that hair dryers cause thinning hair. However, too hot or too much drying may lead to brittle and breakable hair. Let common sense guide you and hold the hair dryer at a normal distance from your scalp and dry to your heart’s content.

Vitamins and Steroids?

Think about this – if you were losing hair because of a lack of vitamins or minerals in your diet, why wouldn’t the back and sides of your head be affected? In actuality, vitamin deficiency results in an even distribution of hair loss all over the head. Of course, it doesn’t hurt to take vitamins on a regular basis for your overall health.

Your follicles width and amount are based on heredity. So claims of hair growing miracle drugs or natural hair loss treatments are untrue.

However, steroids use can cause hair loss. Research has proven that anabolic steroids raise the levels of baldness-inducing male hormones. For those who are genetically prone to hair loss, this can speed up the loss in as little as 3 to 6 months. While this loss may be reversed, it can be permanent.

Sexual Activity to Grow Hair?

Unfortunately, there is no truth to the idea that the more sex you have, the less hair you’ll lose! And the same goes for the rumors that the chemicals released during sex can affect hair loss. Science has yet to uncover any proof to this fantasy. But that doesn’t mean you shouldn’t keep experimenting.

The Hair Loss Family Tree

Many men believe that if their father has a full head of hair, they’ll keep a good head of hair. But hair loss or hair growth is set by a genetic combination determined by both sides of your family.Of course, if your family tree is filled with balding scalps, you do have a better chance of losing hair.

Treatments that work

While hair loss sufferers spend small fortunes on treatments based on myths, there are several proven treatments, non-surgical and surgical.

Currently there are only two non-surgical hair loss treatments that are FDA approved for Hair loss. These two are Propecia (Finasteride) and Rogaine (minoxidil).

Other treatments may or may not help stop or reverse hair loss, but they are not formally approved by the FDA

To learn about proven treatments visit our Hair Loss Solutions section.

Our physician members perform a very refined hair transplant procedure called "Follicular Unit Hair Transplantation". Today there are two methods for doing this procedure. They differ only in the methods used to harvest and prepare the grafts.

Follicular Unit Extraction Video is provided courtesy of Dr. Alan Bauman.

How the follicular unit extraction (FUE) hair transplant procedure is different than standard strip excision hair transplant surgery.

How the minimally invasive hair transplant procedure known as Follicular Unit Extraction or FUE is performed.

How follicular unit grafts are created under microscopic dissection and then placed into tiny incisions in the balding areas.

Crinagen is an all natural alcohol-free topical scalp spray clinically backed to reduce the amount of DHT (dehydrotestosterone) in the scalp. It contains no alcohol, and has displayed no side effects. Crinagen is also equally safe for men and women and is most effective in men and women with thinning hair. In addition to blocking scalp DHT, they both are reported nourish the scalp’s hair follicles. Crinagen usually displays its effects on average in five months.

How It Works:

The product's main ingredients are Saw Palmetto, Zinc, and Azelaic Acid. All 3 ingredients are reported to reduce the production of scalp DHT and nourish the scalp's hair follicles.

Developing Realistic Expectations:

Crinagen has not been clinically proven nor approved by the FDA. Thus, like Revivogen and Tricomin, Crinagen should be used only after seriously considering proven treatments like Propecia (finasteride) and Rogaine (minoxidil).

Don't expect immediate results. It's recommended to use Crinagen for at least 6 to 12 months before determining its effectiveness. Documenting your progress with bi-monthly photos can help you determine whether or not Crinagen is working for you.

Hair shedding is a common symptom the first few months and a sign that the medication may be working for you. It's crucial to push past this stage with continued use for the recommended period of time.

To date, only surgical hair restoration is proven to grow hair in completely bald areas. You are invited to have a free virtual consultation with one of our prescreened hair restoration physicians.