A Thicker Fuller Head of Hair in 30 Seconds?

A staggering 50% of men and 30% of women will experience some degree of thinning hair by the age of 50. Along with state of the art hair transplant surgery and credible drug treatments like Propecia (finasteride) and Rogaine (minoxidil), many balding men (and women) have added credible concealers like Nanogen to their daily treatment regimen.

As the term implies, concealers do not actually regrow hair but rather cosmetically enhance the appearance of balding areas of the scalp by reducing the contrast between scalp and hair color and/or adding fullness to thin, wispy hair follicles.  Nanogen is no exception however, Nanogen is very popular and differs from other topical concealers in several areas.

How Nanogen Works

Nanogen is made of microscopic keratin fibers. Keratin is the same material that natural hair is composed of, giving the product a natural look and feel when applied to existing thinning hair. Unlike other fiber-based hair loss concealers, Nanogen’s “nanofibers” have a patent pending, “dipolar” electrostatic charge coating that causes them to cling to existing hairs in a fashion resembling needles on a Christmas tree rather than lying flat against the follicles. It’s this perpendicular binding that gives what some users have described as an immediate “lift” to the hair.  By increasing the diameter of each individual follicle from root to tip, Nanogen is able to enhance the appearance of hair density resulting in the illusion of a full head of hair.

Applying Nanogen

Nanogen is available in ten different shades. These colors can even be combined to invisibly blend with your natural hair. The fibers are sprinkled onto the balding scalp from an applicator reminiscent of a large pepper shakerand then blended with the fingertips. Once the desired effect is achieved, there is an optional locking mist available to help the fibers stay in place through inclement weather conditions, intense exercise and perspiration.

Users should take care when applying Nanogen near the hairline. Over application can result in accumulation and an unnatural appearance.

Conclusion

Nanogen’s keratin-based nanofibers are an excellent choice for balding men and women wishing to improve the appearance of thinning hair. Unlike some creams, sprays or make-up type concealers, Nanogen fibers are odor-free, non-itchy, wash out easily and won’t stain your clothing or pillowcase. With practice, the application is clean, quick and simple.

See what Real Patients are Saying about DermMatch on our Hair Loss Forum

For an in-depth comparison of Nanogen and similar fiber-based hair loss concealer Toppik, see the discussion topic, Product Review: Nanogen. To see what other members and Nanogen users are saying, you are encouraged to use the "search" feature of our hair restoration discussion forum.

Brilliant Hair Loss Treatment, or is it a Scam?

ElectroTrichoGenesis (ETG), also known as Cosmetic TrichoGenesis (CTG), is a little known hair loss treatment that makes some very lofty hair growth claims. How does ETG work and is it really clinically proven to treat androgenic alopecia(genetic balding)?

How ElectroTrichoGenesis (ETG) Works

ETG is promoted as a safe, painless and non-intrusive. Treatment is administered via an “ergonomically shaped couch with a semi spherical hood” manufactured by Current Technology Corporation in Vancouver, Canada.

The patient reclines on the chair and the hood (with disposable liner) is placed over the head but does not make contact with the scalp. This special hood contains electrodes that deliver “specified pulsed electrostatic energy” delivered passively to the scalp by the low-level electric field generated within it.

ETG is believed to stimulate the regrowth of hair through the positive influence of the pulsed electrostatic field it generates. This field is said to stimulate “changes within the hair bulge and the follicle, stabilizing hair loss and stimulating new hair growth”. Patients receive a single 12 minute session weekly.

Is ETG Clinically Proven?

The following three studies on the efficacy of ElectroTrichoGenesis (ETG) as a treatment for thinning hair have been published in peer-reviewed journals:

Maddin, W. Stuart; Bell, Peter W.; James, John H. M. (1990).
"The Biological Effects of a Pulsed Electrostatic Field with Specific Reference to Hair Electrotrichogenesis". International Journal of Dermatology29(6): 446–450.

Benjamin, Benji; Ziginskas, Danute; Harman, John; Meakin, Timothy (2002).
"Pulsed electrostatic fields (ETG) to reduce hair loss in women undergoing chemotherapy for breast carcinoma: A pilot study". Psycho-Oncology11(3): 244–248

Maddin, WS; Amara, I; Sollecito, WA (1992).
"Electrotrichogenesis: further evidence of efficacy and safety on extended use". International Journal of Dermatology31(12): 878–80

According to the 36-week comparative, controlled study conducted on male subjects at the University of British Columbia and published in The International Journal of Dermatology, 96.7% of those treated experienced cessation of hair loss and/or hair regrowth. Decreased hair loss was seen as early as 4 to 6 weeks but many patients required more time for results.

The pilot study conducted on women undergoing chemotherapy for breast carcinoma and published in  Psycho-Oncology,showed that twelve out of 13 participants had good hair retention throughout the chemotherapy period and afterwards with no reported side effects.

As with the clinically proven medical hair loss treatments Rogaine (minoxidil) and Propecia (finasteride), ETG is said to be most effective in the early stages of balding.

Conclusion

Although the data put forth in this article seems to paint ETG as a clinically proven and highly effective hair loss treatment, it’s important to note that the procedure is not new. The studies referenced above were published more than 13 years ago. If ETG truly works to stimulate hair growth and suppress the advancement of hair loss, why has it not become a fixture in the world’s leading hair restoration clinics? Where are all the glowing, unbiased reviews?

With no reported side effects, there may be no harm in giving ETG a try if there is a provider in your area and the fees are reasonable. However, balding men and women are encouraged to consult with an experienced and reputable hair restoration physicianin order to diagnose the cause of their thinning hair and learn about the outstanding medical and surgical options available today.

Para-Aminobenzoic Acid (PABA) has been called the anti-gray hair vitamin and is considered one of the lesser known members of the vitamin B complex family (despite the fact that it’s not really a vitamin at all).  PABA is a non-protein amino acid and isn’t essential in the human body.  It can be found in foods such as liver, whole grain, yeast, and kidney and is listed as an active ingredient in several popular herbal hair loss treatments such as Provillusfor women and Procerin. 

The potassium salt in PABA called POTABA is available on prescription. POTABA is indicated for Peyronie’s Disease and scleroderma. The dose for Peyronie’s disease and scleroderma is very high (12 grams daily in 4 to 5 distributions) and must only be used under medical supervision. Because of the high doses needed to achieve clinical efficacy, patient compliance is typically poor.

But can PABA actually treat male pattern baldnessor genetic female hair loss?

Some tests conclude that PABA when combined with other elements such as folate, biotin, and pantothenic acid, may restore pre-maturely graying hair to its natural color.  Some anecdotal reports suggest it might also stop hair loss, however; there are at least as many reports that contradict this.  Moreover, we haven’t seen any evidence to suggest it can stimulate new hair growth or hair regrowth.

PABA comes in doses of 100mg, 250mg, and 500mg as a standalone product.  However, since no formal clinical studies have been performed on PABA for hair loss, a suitable dosage is mostly speculation.  Additionally, since no regulations have been placed on herbal medication, one should proceed with extreme caution before taking any herbal supplement.  Consulting with a doctor is advised.

Side Effects and warnings:

Some manufacturers of herbal replacements to medication would have you believe that herbal treatments come without potential side effects.  However, this is a farce. 

The following side effects have been reported from consumers of PABA: Anorexia, vomiting, nausea, hypersensitivity, fever and rash (particularly with larger doses). These symptoms went away when PABA is stopped.

Ironically, Provillusonly includes PABA in the woman’s formula.  However, women should know that pregnant women, nursing mothers, and children should avoid using PABA.

For those with renal disease, PABA should be used with caution.  PABA should be stopped if hypersensitivity develops. Those taking pharmaceutical doses of PABA must be under medical supervision.

Revolutionary Hair Growth Formula?

Anyone suffering the effects of an incurable and debilitating medical condition yearns for the promise of new and revolutionary treatment options and hair loss sufferers are no exception. Though often dismissed as insignificant by those who are unaffected by it, baldness and thinning hair can devastate the lives of millions of men and women susceptible to the effects of androgenic alopecia. The desperation to restore the flowing locks of youth make this demographic particularly susceptible to slick marketing campaigns promising to halt balding and regrow hair. One such product marketed in this fashion is Europe’s TRX2 Molecular Hair Loss Treatment. But, will hair loss sufferers find follicles behind the flash?

TRX2 Ingredients

TRX2 Molecular Hair Loss Treatment is not a drug or medication. It is an herbal, dietary supplement taken orally. A glance at its ingredients list reveals nothing new or revolutionary. Each component is readily available at your local nutritional supplement shop, though you may not find the same concentrations of each in a single product.  It's ingredients are listed below:

Ingredients: L-carnitine tartrate (800 mg), potassium chloride (191 mg), L-leucine (150 mg), isoleucine (75 mg), valine (75 mg), nicotinic acid (40 mg), and biotin (150 µg).

TRX2 Scientific Studies?

With these ingredients so readily available, one might wonder if the significant cost savings of purchasing them individually and mixing your own TRX2 at home is just as effective for hair growth. The official website’s FAQ addresses this notion with the following response.

“The benefit of taking TRX2™ Molecular Hair Growth Supplement singularly, as opposed to buying each ingredient separately, is based on several facts:

The precise amount and ratio of ingredients in our supplement are carefully chosen and engineered based on credible scientific studies. The ingredients in our capsule were specifically formulated to work in concert with one another and are manufactured in accordance with strict European quality controls. For the consumer, the convenience of taking all compounds at the optimum ratio in one capsule and delivered via our proprietary potassium channel stimulating complex is crucially important.”

Perhaps this is true. However, at a hefty €54.95 (about $72) for a one month supply, those seeking to save some money may want to give the home brew option a shot first.

Additionally, referencing scientific studies is an effective way to add legitimacy to a product but one must always consider the source. While the TRX2 website provides detailed data gathered from a “randomized, double-blind, placebo-controlled study”, it is unclear who conducted the study and there is no mention of publication in a peer reviewed journal.  Peer review is the industry standard for evaluation of clinical trial results and its absence is cause for concern.

Does TRX2 Work?

TRX2 claims to stop hair loss and regrow hair through the “rejuvenation of potassium ion channels within hair follicles”. This theory is based on research suggesting that the opening of potassium channels is an important regulatory mechanism for hair growth.

A bold statement at the top of the TRX2 website states that it has been shown to regrow hair in nearly 9 out of 10 men and women. But, does TRX2 really do what it claims? The bottom of the company’s website provides a very important disclaimer.

“These statements have not been evaluated by the medicines regulatory agencies. This product is not a drug or medicine, and is therefore not intended to diagnose, treat, cure or prevent any disease. This patent-pending food supplement contains nutrients that help promote and sustain healthy hair growth. Results may vary and are subject to your individual metabolism. Regarding risks and side-effects please see the package insert and ask your physician or healthcare specialist.”

Careful wording in the above statement may give consumers the wrong idea. Helping to “promote and sustain healthy hair growth” is not the same as stopping hair loss or regrowing hair lost due to the effects of androgenic alopecia. A quality shampoo and condition can make hair more manageable and appear fuller.

TRX2 Side Effects

While TRX2 contains "drug-free" ingredients that are all natural or synthesized as normal metabolites in the human body, there is a potential for certain side effects.

Some consumers of TRX2 have reported transitory gastrointestinal effects including an upset stomach.  Thus, it is recommended to take TRX2 after eating.  Additional side effects include the possibility of allergic reactions such as skin flushes.  If any of these conditions occur, it is recommended to consult a physician.

 It is also recommended that any potential customers suffering from digestive system disorders, diabetes or those who are glucose-intolerant consult with their physician before taking TRX2.

Moreover, pregnant women and nursing mothers should avoid taking TRX2 due to its lack of long term safety data.

Conclusion

The role of potassium channels in hair growth is still being investigated and it’s unclear if TRX2 truly has the potential to significantly affect these channels. However, there is a clinically proven and FDA approved medical hair loss treatment that is known to do so. Rogaine (minoxidil) has been used successfully by balding men and women for more than 20 years. The exact mechanisms by which minoxidil affects hair growth are not fully understood but it is a known vasodilator and has also been shown to enhance the flow of potassium ions. Given that minoxidil is relatively inexpensive, clinically proven and comes with very little risk of side effects, it may be a better option for hair loss suffering men and women.

Additionally, balding men should seriously consider adding Propecia (finasteride) to their hair growth regimen. Propecia stops hair loss  at its core by inhibiting the production of DHT (the hormone responsible for genetic baldness) and is arguably the most effective treatment for male pattern balding currently available.

When it comes to “new and revolutionary” hair loss treatments, proceed with caution. There is nothing wrong with trying a new treatment provided it is safe and purchased from a reliable source. However, forgoing tried and true medical treatment s in favor of experimental products may result in further loss of precious and irreplaceable hair.

To share your thoughts and experience with TRX2 on our hair loss forum, join the discussion “TRX2: Any Feedback?”.

Diffuse Hair Loss and How to Treat It

Unlike male pattern baldness (MPB) and female pattern hair loss (FPHL), which tends to follow one of the hair loss patterns defined by the NorwoodScale and the LudwigScale, Diffuse Patterned Alopecia (DPA) is characterized by diffuse thinning throughout the front, crown and vertex(crown) with no distinct pattern evident. However, like male and female pattern balding,Diffuse Patterned Alopecia patients typically preserve the stable "permanent zone" on the sides and back of the scalp and may sometimes retain a well-defined hairline. DPA is also a type of hereditary balding condition like and rogenetic alopecia (genetic hair loss).

Diffuse Patterned Alopecia (DPA) can be difficult to diagnose and, particularly in its early stages, may be confused with a similar condition known as Diffused Unpatterned Alopecia (DUPA). While both conditions are characterized by diffuse thinning, DUPA sufferers lack the stable permanent zone necessary for surgical hair restoration.

Treatment for Diffuse Patterned Alopecia

DPA often responds well to medical hair loss treatments like Propecia (finasteride) and Rogaine(minoxidil) and, due to the preservation of the permanent donor region, many DPA sufferers are candidates for hairrestoration surgery.

Conclusion

It’s essential that hair loss suffering men and women seeking medical and/or surgical treatment for diffuse thinning consult with a skilled and experienced hair restoration physician. Differentiating between DPA and DUPA is critical because Diffuse Patterned Alopecia patients frequently make good hair transplant candidates, whereas DUPA patients rarely do.